Genetics of Human Infertility (Monographs in Human Genetics Vol 21) – Original PDF from Publisher
by M. Schmid , series editor , and P.H. Vogt , editor
Over 10% of couples globally experience infertility, which is linked to a wide range of extremely variable diseases that are occasionally only detectable in the germ line .
Along with immunological interference, environmental variables, and anatomical anomalies, its complicated etiology frequently, but not always, involves genetic elements .
Genetic abnormalities are probably the only cause of about 30% of cases of infertility .
Therefore, animal knockout models employed in experimentation provide compelling evidence that one or more gene abnormalities can result in sterility. It is difficult to translate such fundamental research findings into clinical investigations
which leaves the great majority of infertile patients with unidentified genetic reasons.
Nevertheless, a great deal of potential genes have been identified by advanced molecular techniques. Written by the foremost experts in the industry, this book offers a thorough introduction to the topic of infertility. It includes both frequent and unusual disorders in addition to fundamental biological,
cytological, and molecular research.
Human geneticists, endocrinologists, epidemiologists, zoologists, and counselors working in the fields of assisted reproduction, infertility, and human genetics should all study it .
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